This full-size SUV splits into two distinct stories. The first-generation trucks with the 4.6L V8 were unkillable, owners routinely hit 400k-500k miles with nothing but oil changes, but rust ate the bodies and air suspension failures totaled otherwise healthy trucks. The current generation (2018-2024) offers serious space, strong towing, and genuine family comfort, but the 10R80 transmission is a documented weak point: multiple owners report rebuilds or replacements before 100k miles at $7k-10k out of pocket. If you're buying used in the 60k-100k mile range, budget for transmission work or get an extended warranty that covers it. The 2025-2026 redesign brings a polarizing oblong steering wheel and touch-heavy controls that owners either adapt to or never stop resenting. Buy this if you need the space and towing capacity, can afford the warranty, and don't mind that it drives more like a truck than a luxury cruiser. Walk if you're stretching the budget or buying high-mileage without coverage.
The GX460 was Lexus's bulletproof V8 swan song, silky, plush, and routinely hitting 200k miles with minimal drama. The 2024 redesign swapped that proven engine for a twin-turbo V6 that tows hard but drinks just as much fuel, then wrapped it in a cheaper interior that owners call 'un-Lexus-like' and plagued the first year with brake squeal (8+ month backorder on parts), hood flutter, and falling headliners. If you need genuine off-road capability or 9,000-lb towing, the GX550 delivers; if you want the on-road luxury the badge promises at this price, a lightly used GX460 or a German unibody will leave you happier.